Table of Contents
Definition #
- Bilateral pars interarticularis fracture of C2 with anterior displacement (spondylolisthesis) of C2 on C3.
- Also called traumatic spondylolisthesis of the axis.
Mechanism of injury #
- Extension + axial loading (classic).
- Flexion-distraction (Type IIA).
- Flexion + compression / distraction in unstable cases.
The Levine-Edwards classification (the modified Effendi classification) #
- Type I: Vertical pars fracture, ≤ 3 mm displacement, stable.
- Type IA (atypical): Non-parallel bilateral fractures, may involve foramen transversarium.
- Type II: Pars fracture + C2–C3 disc/PLL disruption, > 3 mm displacement, some angulation.
- Type IIA: Oblique fracture, flexion-distraction; traction dangerous.
- Type III: Type II + bilateral C2–C3 facet dislocation; ALL may be injured.

Imaging #
- X-ray: lateral/AP/odontoid views, upright films for displacement.
- CT: gold standard for fracture pattern and displacement.
- MRI: evaluate C2–C3 disc, ligaments, cord, vertebral artery involvement.
Stability Criteria #
- 3–5 mm anterior translation of C2 on C3.
- 10° angulation between C2–C3.
- Disc/PLL/ALL disruption.
- Facet dislocation.
- Atypical line through foramen transversarium → vertebral artery risk.
Treatment #
Nonoperative (stable types):
- Type I, IA → rigid collar 8–12 weeks.
- Type II (minimal displacement/angulation) → collar or halo.
Operative (unstable or failed conservative):
- Type II (> 5 mm translation or > 10° angulation).
- Type IIA → halo (select) or surgery (fusion preferred).
- Type III → posterior C2–C3 fusion (± anterior).
- Surgical options:
- Posterior C2 pedicle + C3 lateral mass screws.
- ACDF at C2–C3 if major disc injury.
- Combined anterior + posterior for severe instability.
Prognosis #
- Type I: > 95% union with collar.
- Type II/IIA/III: higher nonunion risk, often need surgery.
- Mortality/morbidity low if treated appropriately.
Complications #
- Nonunion or malunion (esp. IIa/III).
- Neurological injury (rare, but risk in atypical, IIa, III).
- Vertebral artery injury (if foramen transversarium involved).
- Immobilization issues: halo pin infections, skin sores, pulmonary issues.
Key Points (WFNS & reviews) #
- CT = first-line imaging; MRI if ligament/disc/cord concerns.
- Rigid collars often preferred over halo (fewer complications).
- Surgery recommended for Type IIA, III, or unstable II.
- Elderly: individualized approach (halo poorly tolerated).
